This dataset offers single-cell RNA sequencing data for the Heart, Liver, and Kidney of domestic pigs, profiled at four key time points: Days 21, 50, 100, and 180. These three organs represent the primary targets in xenotransplantation, where the pig has emerged as the most promising donor species due to its physiological compatibility with humans. Ongoing achievements in cardiac, hepatic, and renal xenotransplantation across preclinical and clinical settings emphasize the value of comprehensive, high-resolution cellular profiling of these organs.
This module delivers a detailed cellular landscape of these organs across maturation, enabling the investigation of cell-type composition, developmental trajectories, and regulatory programs that influence graft performance and immunological compatibility.